Capabilities

We are based in a new purpose built facility opened in early 2002. This contains modern synthetic laboratories equipped with a range of fumehoods, including a hydrogen fluoride handling hood and two 'walk-in' hoods.

We have a 250 MHz multinuclear nmr spectrometer and GC 'in-house'.

Our expertise in organic chemistry includes complex multi-step synthesis of high quality intermediates, and fluorination of organic molecules. We generally work on scales ranging from 100 mg to 5 kg.

We specialise in:
• High pressure autoclave reactions
• Fluorination

We offer the following services:
• Custom Synthesis, including design of new routes to synthetic targets.
• Contract Research
• Catalogue Support

Facilities

• Full range or standard glassware (5 ml - 20 litre)
       mg scale research - kg scale development
• 10 litre rotary evaporator
• Glass/stainless steel vacuum lines
       Corrosive gas handling, gas bottling, low temperature trap to trap distillation
• High pressure autoclaves (50 ml - 2 litre)
       Up to 100 bar, 250 ^oC

• Analysis
       In-house facilities include capillary GC and 250 MHz multinuclear
       NMR spectrometer (¹H, ¹³C, ¹⁹F and ³¹P)
       We have good access to specialised techniques such as mass spectrometry,
       GC-MS, LC-MS and elemental analysis at local universities

• Sulfur tetrafluoride and anhydrous hydrogen fluoride 'on tap'

What types of chemistry do we perform?
	• Acetylation • Acid chlorides • Acylation • Aldol condensation • Alkylation • Amide formation • Amide hydrolysis • Amination • Benzoylation • Bromination • Butyl lithium reactions • Cyanide formation • Cyclisation • Dehalogenation • Decarboxylation • Diazotisation		• Esterification • Fluorination • Halogen exchange • High pressure reactions • High temperature reactions • Hydrogenation • Lithiation • Methylation • Nitration • Optical resolution • Organometallic reactions • Palladium transfer reactions • Phase transfer reactions • Photohalogenation • Reductions • Sulfonation