Fluorination technology

Are fluorination reactions often avoided in your research and development laboratories due to safety concerns? Would you like to try a fluorination reaction, but cannot do so because you do not have the resources to invest in expensive equipment for a small scale reaction? Many fluorination reagents are highly toxic, corrosive, gaseous and difficult to manipulate, hence special apparatus is often required. Nevertheless, we at Manchester Organics are able to carry out a whole range of conversions on mg to kg scales

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Examples of site-selective fluorination offered by Manchester Organics

1. Sulfur tetrafluoride

2. Diethylaminosulfur trifluoride (DAST)

3. HF.Pyridine complex

4. Baltz-Schiemann

5. Halogen exchange

6. Electrophilic fluorinations using reagents of the N-F class

7. (Perfluoroalkyl) trimethylsilanes

DAST and HF.Pyridine are two particularly useful reagents which are manufactured in-house and can be supplied to order.