Facilities
UK
At our Runcorn site in the UK, we can utilise 55 fume hoods including 15 walk-in hoods, spread across six laboratories. Our high pressure facility has three separate blast bays which are routinely employed for hydrogenation, carbonylation and fluorination.
- AVANCE III HD 400 NMR Spectrometer
- Vessel sizes up to 20 L (glass, stainless steel, Monel and Hastelloy)
- Capabilities from mg to multi-kg production
- Operational temperature ranges from -100 °C to 250 °C
- UV spectrophotometer
- MLS microwave reactor
- Radleys carousels and Biotage Isolera automated chromatography system for rapid screening and purification
- Online literature search facilities
- Quality control laboratory
- Large range of catalogue items in stock, as well as rapid turnaround of bespoke compounds
- Synthetic pathways can be designed, developed and delivered in their entirety
- Expertise in a range of fluorination strategies, which can be used on a variety of different molecules with wide functional group tolerance
India
R&D Operations
- Total of 27,000 sq ft laboratory facilities, including walk-in fume hoods
- Two laboratories for organic synthesis
- One laboratory for inorganic synthesis
- Continuous vapor phase fluorination laboratory
- High pressure laboratory
- Operational temperature ranges from -78 °C to 400 °C
- Online literature search facilities
Non-GMP Plant, Surat
- Total reactor volume 1.6 KL
- Skid mounted systems with 8 reactors comprising of glass, MSGL, SS316 and Inconel
- SS316 and MSGL distillation systems
- SS316 and Inconel autoclaves
- Halex facility
- Operational temperature ranges from -20 °C to 300 °C
- High vacuum (down to 5 mmHg) distillation
- High pressure reactions up to 30 bar
- In-house Hazop studies before process scale up
- Capabilities for inert atmosphere, low temperature reactions, etc.
cGMP Pilot Plant, Dewas
Since being commissioned in 2011, our flagship cGMP plant has expanded our capacity and capability. This state-of-the-art facility contains glass-lined reactors as well as large-scale high-pressure fluorination vessels up to 1.5 kL.
Multi-Production Plant (MPP), Surat
- Total reaction area - 1036 m2 distillation area - 1100 m2
- Material of construction includes glass, MSGL, SS316 and Inconel
- Operational temperature ranges from -20 °C to 300 °C
- High vacuum (down to 5 mmHg) distillation
- High pressure reactions (up to 30 bar)
- Distillation capabilities include both azeotropic and fractional batch distillations with total volume - 30 m3 cooling capacity - 1000 TR, chilling capacity - 100 TR and heating capacity - 1.2 MKcal/h
- Capabilities for reactions including halex, diazotization, halogenations (fluorination, bromination and chlorination), hydrolysis, hydrogenation, nitration reactions, etc.